If A is the sister of B, B is the brother of C, and C is the father of D, then how is A related to D?

If A is the brother of B, B is the sister of C, C is the daughter of D, and D is the father of E, then how is A related to E?

If A is the mother of B, C is the father of D, B is the sister of D, and E is the son of C, then how is A related to E?

If A is the father of B, C is the mother of D, B is the brother of D, and E is the son of A, then how is E related to C?

If A is the father of B, C is the mother of D, B is the brother of C, and E is the son of D, then how is A related to E?

If A is the sister of B, C is the brother of D, B is the daughter of C, and E is the son of A, then how is E related to D?